BLOOD THINNERS AND DIET: A DELICATE BALANCE
Drug Metabolism of blood thinners:
Warfarin are primarily metabolized by the liver’s cytochrome P450 (CYP) enzymes system. This CYP
enzyme system include CYP2C9, CYP1A2, CYP3Ad, and CYP2C19. These enzymes breakdown the drug into inactive metabolites which are excreted from the body. But metabolism for different thinners are different from others as newer thinner like dabigatran and apixaban have different metabolic pathways. Certain foods, particularly vitamin K rich, can interfere the effectiveness of blood thinners. Spinach and kale are prime examples.
Foods to embrace: Your Drug Allies
Lean Proteins:
Chicken, Fish, Beans and Tofu.
Whole grains:
Brown rice, Quinoa, whole wheat bread provide fiber and essential nutrients
Healthy fats:
Avocados, Nuts, and Olive Oil are some good examples.
Foods to excuse: Temporary farewell
Leafy Green Vegetables: Spinach, Kale and Collard greens are high in vitamin K.
Cruciferous vegetables: Broccoli, Cauliflower, Brussels Sprouts contain vitamin K.
Some oils as Soybeans, Canola and Green tea also effect thinners metabolism.
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